Center for Neurocognitive Outcomes Improvement Research

Noninvasive imaging and simultaneous brain stimulation

Functional MRI (fMRI) is the dominant method for measuring brain activity in the cognitive neurosciences. We use fMRI to accomplish several basic and applied research goals. Using specialized memory tasks, we investigate how brain areas like the hippocampus participate within large-scale networks to support memory abilities. We also use network-based analysis to target specific brain areas with noninvasive brain stimulation. fMRI is also used to understand how stimulation affects brain function, and as a biomarker to assess the ability to affect specific areas in targeted stimulation interventions. We also perform brain stimulation with TMS during the simultaneous acquisition of fMRI, to investigate the immediate impact on brain function.

Read about our various findings on the Publications page or check out these representative studies:

Enhanced reinstatement of naturalistic event memories due to hippocampal-network-targeted stimulation

Evidence for immediate enhancement of hippocampal memory encoding by network-targeted theta-burst stimulation during concurrent fMRI

Above: The MRI-compatible TMS wand, peaking out from inside the scanner bore.

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